منابع مشابه
A model of the proton translocation mechanism of complex I.
Despite decades of speculation, the proton pumping mechanism of complex I (NADH-ubiquinone oxidoreductase) is unknown and continues to be controversial. Recent descriptions of the architecture of the hydrophobic region of complex I have resolved one vital issue: this region appears to have multiple proton transporters that are mechanically interlinked. Thus, transduction of conformational chang...
متن کاملTowards the molecular mechanism of respiratory complex I.
Complex I (NADH:quinone oxidoreductase) is crucial to respiration in many aerobic organisms. In mitochondria, it oxidizes NADH (to regenerate NAD+ for the tricarboxylic acid cycle and fatty-acid oxidation), reduces ubiquinone (the electrons are ultimately used to reduce oxygen to water) and transports protons across the mitochondrial inner membrane (to produce and sustain the protonmotive force...
متن کاملI-17: The Mechanism of Gonadal Sex Determination
Background In mammals, a single exon gene SRY on the Y-chromosome is activated in the XY gonadal primordium and initiates a cascade of molecular and morphological events leading to testicular differentiation. SRY-encoded protein (SRY) is a transcription factor harboring a HMG-box DNAbinding motif that upregulates SOX9, which encodes another transcription factor sharing the DNA binding motif wit...
متن کاملSynchronization analysis of complex dynamical networks with hybrid coupling with application to Chua’s circuit
Complex dynamic networks have been considered by researchers for their applications in modeling and analyzing many engineering issues. These networks are composed of interconnected nodes and exhibit complex behaviors that are resulted from interactions between these nodes. Synchronization, which is the concept of coordinated behavior between nodes, is the most interested behavior in these netwo...
متن کاملApplication of dimeric ortho-palladated complex of 2-methoxyphenethylamine in the Heck coupling reaction
The application of the [Pd{C6H3(CH2CH2NH2)-4-OMe-5-κ2-C,N}(μ-Br)]2 complex of 2-methoxyphenethylamine in the Heck coupling reaction was considered under both conventional and microwave irradiation conditions, and their results were compared. This complex is an efficient, stable and non-sensit...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2018
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2018.09.030